DegronMD - Q3B8N2(LGALS9B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G28E	TCGA-A7-A0D9	BRCA	TCGA	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28E	TCGA-D3-A3C7	SKCM	TCGA	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28E	DO4128	BRCA	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28E	DO222908	MELA	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28E	DO47569	SKCM	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.T51M	TCGA-D1-A17U	UCEC	TCGA	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0556
p.T51M	TCGA-HU-A4H8	STAD	TCGA	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0556
p.T51M	DO47869	STAD	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0556
p.T51M	DO41887	UCEC	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0556
p.V37I	TCGA-VQ-A8P2	STAD	TCGA	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.7076
p.V37I	DO51761	STAD	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.7076
p.S40C	DO50982	LAML	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.7541
p.S40C	DO228967	LICA	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation altering degron motif	0.7541
p.T43N	DO229024	LICA	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.2778
p.A36T	DO229052	LICA	ICGC	VLSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons