DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
C11orf91
UniProt ID:
Q3C1V1
Entrez ID:
100131378
Protein name:
Uncharacterized protein C11orf91
External links:
UniprotKB
HGNC
RefSeq
COSMIC
Please click
HERE
for better display.
Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
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GO - Biological processes (BP):
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GO - Molecular function (MF):
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GO - Cellular component (CC):
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Choose a PDB ID:
Open in full screen with detailed sequence annotations
C11orf91
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AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.S14I
DO224566
LUSC
ICGC
PPLY
ITCH
19:22
Mutation rewiring degron network
0.1944
p.A18P
SIDM00762
Non-Small Cell Lung Carcinoma
GDSC
PPLY
ITCH
19:22
Mutation rewiring degron network
0.3056
p.Y27S
ACH-000846
Head and Neck Cancer
CCLE
PPLY
ITCH
19:22
Mutation rewiring degron network
0.1944
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for C11orf91 in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc