DegronMD - Q53QW1(TEX44)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T189A	SIDM01016	T-Lymphoblastic Leukemia	GDSC	AASTT	DEG_SPOP_SBC_1	186:190	Mutation altering degron motif	0.7139
p.T189A	SIDM01263	T-Lymphoblastic Leukemia	GDSC	AASTT	DEG_SPOP_SBC_1	186:190	Mutation altering degron motif	0.7139
p.T189A	Jurkat	haematopoietic and lymphoid tissue	COSMIC	AASTT	DEG_SPOP_SBC_1	186:190	Mutation altering degron motif	0.7139
p.A32T	SIDM00606	Squamous Cell Lung Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	36:40	Mutation rewiring degron network	0.2222
p.A32T	KNS-62	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	36:40	Mutation rewiring degron network	0.2222
p.A178V	SIDM00145	T-Lymphoblastic Leukemia	GDSC	AASTT	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.1111
p.A178V	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	AASTT	DEG_SPOP_SBC_1	186:190	Mutation rewiring degron network	0.1111
p.D67E	SIDM01412	Oral Cavity Carcinoma	GDSC	AISTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons