DegronMD - Q5JQS6(GCSAML)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S62R	TCGA-37-3792	LUSC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.G63A	TCGA-99-8032	LUAD	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.0833
p.D42Y	TCGA-A5-A1OF	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.D44G	TCGA-AJ-A3EL	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.S52F	TCGA-AX-A3G9	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.7982
p.S52F	DO233253	GACA	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.7982
p.D44Y	TCGA-B5-A1MR	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.E49D	TCGA-D1-A16X	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.3056
p.E57K	TCGA-D3-A8GM	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.25
p.E57K	TCGA-EE-A2MS	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.25
p.E57K	TCGA-FR-A729	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.25
p.N55D	TCGA-D3-A8GQ	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.3056
p.S54F	TCGA-EB-A6QY	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.9093
p.D42G	TCGA-EY-A1GI	UCEC	TCGA	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.S49T	DO51630	CESC	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.3056
p.S49T	SNU-1040	large intestine	COSMIC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.3056
p.G56D	DO222755	COCA	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2778
p.G56D	C-4-I	cervix	COSMIC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2778
p.E58D	DO10880	GBM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.G44D	DO50970	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.R51K	DO50800	LIRI	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.7237
p.T62N	DO24467	LUAD	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.R48Q	DO231043	LUSC	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2778
p.L63H	DO231183	LUSC	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.0833
p.S51G	DO26526	LUSC	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.5882
p.N53K	DO27389	LUSC	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.6918
p.S62F	DO220857	MELA	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.H42Y	DO222542	MELA	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.H42Y	DO47569	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.S48F	DO37802	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2778
p.E58K	DO37766	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.E58K	DO37406	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.P44L	DO37412	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.L50M	DO47407	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.711
p.S51P	ACH-001549	Lung Cancer	CCLE	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.5641
p.C48S	HCC1569	breast	COSMIC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2778
p.S61T	SNU-1040	large intestine	COSMIC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1389
p.V51A	SNU-C2B	large intestine	COSMIC	VSSTS	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.6936

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GCSAML

UniProt ID: Q5JQS6

Entrez ID: 148823

Protein name: Germinal center-associated signaling and motility-like protein

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for GCSAML in