DegronMD - Q5SRE5(NUP188)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E1540D	TCGA-A5-A0G2	UCEC	TCGA	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.1111
p.E1540D	DO41235	UCEC	ICGC	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.1111
p.A1528V	TCGA-A6-6653	COAD	TCGA	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation altering degron motif	0.5825
p.A1528V	DO10373	COAD	ICGC	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation altering degron motif	0.5825
p.A1536T	TCGA-EC-A1QX	UCEC	TCGA	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.2222
p.A1536T	DO42592	UCEC	ICGC	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.2222
p.S1526F	SIDM00315	Glioblastoma	GDSC	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.2778
p.S1526F	ACH-000570	Brain Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.2778
p.S1526F	YKG-1	central nervous system	COSMIC	APSSS	DEG_SPOP_SBC_1	1528:1532	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons