DegronMD - Q5SSJ5(HP1BP3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E101K	TCGA-CF-A1HR	BLCA	TCGA	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.0556
p.E101K	DO469	BLCA	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.0556
p.E92K	TCGA-CV-5970	HNSC	TCGA	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.3056
p.E92K	DO14280	HNSC	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.3056
p.S90L	TCGA-E6-A1LX	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.S90L	TCGA-EY-A1GI	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.S90L	TCGA-FR-A726	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.S90L	DO48665	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.S90L	DO41020	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.S90L	DO41211	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation altering degron motif	0.7667
p.E82D	DO234470	ESAD	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.A93E	DO229035	LICA	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.2778
p.E99K	DO229050	LICA	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1111
p.V99L	DO37901	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1111
p.R92I	NCI-H23	lung	COSMIC	PATSS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons