DegronMD - Q5SXM8(DNLZ)

DNLZ

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P161L	TCGA-90-A4ED	LUSC	TCGA	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161L	TCGA-AZ-6601	COAD	TCGA	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161L	TCGA-VR-A8EQ	ESCA	TCGA	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161L	DO8119	COAD	ICGC	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161L	DO45482	LUSC	ICGC	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161S	TCGA-90-A4ED	LUSC	TCGA	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.P161S	DO45482	LUSC	ICGC	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.25
p.A154T	DO229010	COCA	ICGC	APTST	DEG_SPOP_SBC_1	154:158	Mutation altering degron motif	0.7139
p.A154T	DO228941	LICA	ICGC	APTST	DEG_SPOP_SBC_1	154:158	Mutation altering degron motif	0.7139
p.E165K	SIDM00232	Kidney Carcinoma	GDSC	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.1389
p.A160V	SIDM01608	Endometrial Carcinoma	GDSC	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.2778
p.A160V	ACH-000990	Endometrial/Uterine Cancer	CCLE	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.2778
p.A144T	ACH-002680	Brain Cancer	CCLE	APTST	DEG_SPOP_SBC_1	154:158	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc