DegronMD - Q5T0L3(SPATA46)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P53S	SIDM00363	Acute Myeloid Leukemia	GDSC	PPQY	ITCH	53:56	Mutation altering degron motif	0.6752
p.P53S	P31-FUJ	haematopoietic and lymphoid tissue	COSMIC	PPQY	ITCH	53:56	Mutation altering degron motif	0.6752
p.R62K	SIDM00783	Colorectal Carcinoma	GDSC	PPQY	ITCH	53:56	Mutation rewiring degron network	0.1667
p.R62K	HCT-116	large intestine	COSMIC	PPQY	ITCH	53:56	Mutation rewiring degron network	0.1667
p.G64E	SIDM01561	Melanoma	GDSC	PPQY	ITCH	53:56	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons