DegronMD - Q5VTQ0(TTC39B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E116D	DO1219	BRCA	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.1667
p.E116D	DO43907	UCEC	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.1667
p.V122A	DO233764	GACA	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation altering degron motif	0.5825
p.N122K	DO229045	LICA	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation altering degron motif	0.6918
p.G135V	DO26647	LUSC	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.0833
p.Q132H	DO42793	UCEC	ICGC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.1667
p.Y130C	ACH-000990	Endometrial/Uterine Cancer	CCLE	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.2222
p.Q117H	L-540	haematopoietic and lymphoid tissue	COSMIC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.1944
p.A130T	SNU-1040	large intestine	COSMIC	VSSSS	DEG_SPOP_SBC_1	122:126	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons