DegronMD - Q5VTT5(MYOM3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P832A	TCGA-BG-A0MS	UCEC	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1944
p.R814W	TCGA-CG-5733	STAD	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.0556
p.R814W	TCGA-G4-6628	COAD	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.0556
p.G831W	TCGA-D3-A2J6	SKCM	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.2222
p.A830V	TCGA-D5-6930	COAD	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.25
p.P825S	TCGA-DX-AB2E	SARC	TCGA	PPLY	ITCH	824:827	Mutation altering degron motif	0.6752
p.T834I	TCGA-IB-7651	PAAD	TCGA	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1389
p.A831V	DO10550	COAD	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.2222
p.R815W	DO10132	COAD	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.0833
p.R815W	DO38551	STAD	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.0833
p.P833T	DO229034	LICA	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1667
p.L821M	DO229035	LICA	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.25
p.T835I	DO46657	PAAD	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1111
p.P826S	DO220073	SARC	ICGC	PPLY	ITCH	824:827	Mutation altering degron motif	0.6752
p.G832W	DO37901	SKCM	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1944
p.P833A	DO41855	UCEC	ICGC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1667
p.M828I	SIDM00303	Ovarian Carcinoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM00907	Burkitt's Lymphoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM00359	Colorectal Carcinoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM01460	Glioma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM01368	Gastric Carcinoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM01575	Plasma Cell Myeloma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	SIDM00159	Biliary Tract Carcinoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	CA46	haematopoietic and lymphoid tissue	COSMIC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.M828I	JHOS-4	ovary	COSMIC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.3056
p.V819M	SIDM00084	Glioblastoma	GDSC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1944
p.V819M	ACH-000376	Brain Cancer	CCLE	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1944
p.V819M	SF295	central nervous system	COSMIC	PPLY	ITCH	824:827	Mutation rewiring degron network	0.1944

Kaplan plot for MYOM3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MYOM3

UniProt ID: Q5VTT5

Entrez ID: 127294

Protein name: Myomesin-3 (Myomesin family member 3)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MYOM3 in