DegronMD - Q5VXM1(CDCP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R288S	TCGA-18-3407	LUSC	TCGA	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.R288S	DO26454	LUSC	ICGC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.P291L	TCGA-90-7767	LUSC	TCGA	PPGY	ITCH	290:293	Mutation altering degron motif	0.7582
p.P291L	TCGA-D1-A2G5	UCEC	TCGA	PPGY	ITCH	290:293	Mutation altering degron motif	0.7582
p.P291L	DO26692	LUSC	ICGC	PPGY	ITCH	290:293	Mutation altering degron motif	0.7582
p.P291L	DO40918	UCEC	ICGC	PPGY	ITCH	290:293	Mutation altering degron motif	0.7582
p.R288C	TCGA-XF-AAMQ	BLCA	TCGA	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.R288C	DO51934	BLCA	ICGC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.R288C	DO234350	ESAD	ICGC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.C283Y	DO230311	COCA	ICGC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.1389
p.R282H	SIDM00407	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.1111
p.R288H	SIDM00534	Colorectal Carcinoma	GDSC	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.R288H	ACH-000986	Colon/Colorectal Cancer	CCLE	PPGY	ITCH	290:293	Mutation rewiring degron network	0.2778
p.D301N	ACH-001569	Skin Cancer	CCLE	PPGY	ITCH	290:293	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons