DegronMD - Q5VY43(PEAR1)

PEAR1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y817C	TCGA-B0-5700	KIRC	TCGA	PPSY	ITCH	810:813	Mutation rewiring degron network	0.2222
p.Y817C	DO19268	KIRC	ICGC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.2222
p.S821N	TCGA-EO-A22R	UCEC	TCGA	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.S821N	DO42713	UCEC	ICGC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.S821G	TCGA-FD-A6TI	BLCA	TCGA	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.S821G	DO49764	BLCA	ICGC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.S821G	SIDM00232	Kidney Carcinoma	GDSC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.S821G	NCC021	kidney	COSMIC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.N819I	TCGA-FF-8042	DLBC	TCGA	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1667
p.N819I	DO222306	DLBC	ICGC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1667
p.Y804H	DO233791	GACA	ICGC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1667
p.P807S	SIDM01293	Colorectal Carcinoma	GDSC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.25
p.S821T	SIDM00362	Burkitt's Lymphoma	GDSC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.1111
p.G801S	SIDM00699	Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.0833
p.G801S	ACH-001138	Lung Cancer	CCLE	PPSY	ITCH	810:813	Mutation rewiring degron network	0.0833
p.G801S	NCI-H2141	lung	COSMIC	PPSY	ITCH	810:813	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc