DegronMD - Q5VZ52(MORN5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D149Y	TCGA-A5-A2K5	UCEC	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.0556
p.D149Y	DO41379	UCEC	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.0556
p.R141H	TCGA-AJ-A3BH	UCEC	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	TCGA-CJ-4907	KIRC	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	TCGA-ED-A82E	LIHC	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	TCGA-HU-A4H3	STAD	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	DO233882	GACA	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	DO19743	KIRC	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	DO48481	LIHC	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	DO47903	STAD	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.R141H	DO41638	UCEC	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2778
p.A146T	TCGA-AX-A3G9	UCEC	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.1389
p.A146T	DO41241	UCEC	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.1389
p.A146T	SIDM00217	Colorectal Carcinoma	GDSC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.1389
p.A146T	ACH-000999	Colon/Colorectal Cancer	CCLE	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.1389
p.A146T	SNU-1040	large intestine	COSMIC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.1389
p.R133S	TCGA-EM-A3SZ	THCA	TCGA	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2222
p.R133S	DO48129	THCA	ICGC	DYR	CBL_MET	137:139	Mutation rewiring degron network	0.2222
p.T132M	DO233944	GACA	ICGC	DYR	CBL_MET	137:139	Mutation blocking phosphorylation signal	0.6389

Kaplan plot for MORN5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MORN5

UniProt ID: Q5VZ52

Entrez ID: 254956

Protein name: MORN repeat-containing protein 5

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MORN5 in