DegronMD - Q6IPT2(GARIN5A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R22S	TCGA-77-8140	LUSC	TCGA	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.25
p.R22S	DO26834	LUSC	ICGC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.25
p.P24Q	TCGA-EE-A2MK	SKCM	TCGA	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.1944
p.P24Q	TCGA-FS-A1ZB	SKCM	TCGA	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.1944
p.P24Q	DO37886	SKCM	ICGC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.1944
p.P24Q	DO38177	SKCM	ICGC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.1944
p.P7T	DO50847	LICA	ICGC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.1111
p.I21T	DO229151	THCA	ICGC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.2778
p.P14S	SIDM00006	Other Solid Cancers	GDSC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.3056
p.P14S	ACH-001552	Skin Cancer	CCLE	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.3056
p.P14S	MCC26	skin	COSMIC	PGTSS	DEG_SPOP_SBC_1	15:19	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons