DegronMD - Q6IQ49(SDE2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M244V	TCGA-CR-7374	HNSC	TCGA	APSTS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2778
p.M244V	DO15334	HNSC	ICGC	APSTS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2778
p.A248S	TCGA-NJ-A4YQ	LUAD	TCGA	APSTS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1667
p.A248S	DO218944	LUAD	ICGC	APSTS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1667
p.A248D	DO229028	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1667

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons