DegronMD - Q6ISU1(PTCRA)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R187C	TCGA-DI-A1BU	UCEC	TCGA	PATTT	DEG_SPOP_SBC_1	182:186	Mutation rewiring degron network	0.3056
p.S193F	DO233146	GACA	ICGC	PATTT	DEG_SPOP_SBC_1	182:186	Mutation blocking phosphorylation signal	0.5833
p.P182L	DO222491	MELA	ICGC	PATTT	DEG_SPOP_SBC_1	182:186	Mutation altering degron motif	0.7582
p.D189N	SIDM00889	Cervical Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	182:186	Mutation rewiring degron network	0.25
p.D174N	ACH-001333	Cervical Cancer	CCLE	PATTT	DEG_SPOP_SBC_1	182:186	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons