DegronMD - Q6NXT4(SLC30A6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S383P	TCGA-13-A5FT	OV	TCGA	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.1389
p.W376C	TCGA-62-A46O	LUAD	TCGA	PVTST	DEG_SPOP_SBC_1	372:376	Mutation altering degron motif	0.7
p.S365F	TCGA-A5-A0G2	UCEC	TCGA	PVTST	DEG_SPOP_SBC_1	372:376	Mutation substituting flanking lysine	0.25
p.A380S	SIDM01778	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.2222
p.P385A	ACH-000748	Bone Cancer	CCLE	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.0833
p.P385A	SJSA-1	bone	COSMIC	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.0833
p.N385I	NCI-H526	lung	COSMIC	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.0833
p.P362A	SJSA-1	bone	COSMIC	PVTST	DEG_SPOP_SBC_1	372:376	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons