DegronMD - Q6P4D5(PABIR3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A19T	TCGA-AX-A0J1	UCEC	TCGA	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.A19T	TCGA-B5-A3FC	UCEC	TCGA	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.A19T	DO49439	PACA	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.A19T	DO41871	UCEC	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.A19T	DO41199	UCEC	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.F10L	TCGA-BR-4362	STAD	TCGA	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.2222
p.F10L	DO38336	STAD	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.2222
p.R23Q	DO44295	CESC	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.1944
p.L18F	DO229019	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation altering degron motif	0.6981
p.S19F	DO37410	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056
p.K5N	ACH-001550	Skin Cancer	CCLE	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation substituting flanking lysine	0.1944
p.K5N	MCC13	skin	COSMIC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation substituting flanking lysine	0.1944
p.S19P	HT-115	large intestine	COSMIC	PSSTT	DEG_SPOP_SBC_1	14:18	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons