DegronMD - Q6PI77(BHLHB9)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S239F	TCGA-05-4430	LUAD	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2222
p.S239F	DO23750	LUAD	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2222
p.S235C	TCGA-10-0930	OV	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.1111
p.S235C	DO32113	OV	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.1111
p.A241E	TCGA-BA-5557	HNSC	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2778
p.A241E	DO15535	HNSC	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2778
p.A252S	TCGA-BP-4963	KIRC	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.1667
p.A252S	DO20653	KIRC	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.1667
p.F233C	TCGA-EO-A22R	UCEC	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.0556
p.F233C	DO42713	UCEC	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.0556
p.A250S	TCGA-ER-A42H	SKCM	TCGA	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2222
p.A250S	DO223909	SKCM	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.2222
p.E254D	DO223122	ESCA	ICGC	PPSY	ITCH	243:246	Mutation rewiring degron network	0.1111
p.P244T	DO51474	PACA	ICGC	PPSY	ITCH	243:246	Mutation altering degron motif	0.7031

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons