DegronMD - Q6T310(RASL11A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D27N	TCGA-44-2662	LUAD	TCGA	PESSS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1389
p.D27N	DO26290	LUAD	ICGC	PESSS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1389
p.K26N	DO228952	LICA	ICGC	PESSS	DEG_SPOP_SBC_1	16:20	Mutation substituting flanking lysine	0.2778
p.G8R	DO50798	LIRI	ICGC	PESSS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1111
p.S20T	SIDM00683	Prostate Carcinoma	GDSC	PESSS	DEG_SPOP_SBC_1	16:20	Mutation altering degron motif	0.6005
p.S20T	ACH-000977	lymph node	CCLE	PESSS	DEG_SPOP_SBC_1	16:20	Mutation altering degron motif	0.6005
p.M6V	ACH-000985	Colon/Colorectal Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	16:20	Mutation substituting flanking lysine	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons