DegronMD - Q6TDP4(KLHL17)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P629S	TCGA-B7-5816	STAD	TCGA	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1111
p.P629S	DO38599	STAD	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1111
p.S631F	TCGA-EB-A299	SKCM	TCGA	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1667
p.S631F	DO37794	SKCM	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1667
p.P629L	TCGA-HG-A9SC	CESC	TCGA	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1111
p.P629L	DO51603	CESC	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.1111
p.P633L	TCGA-HQ-A5NE	BLCA	TCGA	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.2222
p.P633L	DO51900	BLCA	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.2222
p.V637M	DO228935	COCA	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation altering degron motif	0.7208
p.T634M	DO223038	ESCA	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.25
p.P628L	DO229054	LICA	ICGC	VSSTS	DEG_SPOP_SBC_1	637:641	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons