DegronMD - Q6UWN5(LYPD5)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D106V	TCGA-A3-3317	KIRC	TCGA	PPDY	ITCH	94:97	Mutation rewiring degron network	0.0833
p.T105A	TCGA-D1-A15X	UCEC	TCGA	PPDY	ITCH	94:97	Mutation rewiring degron network	0.1111
p.G89S	DO1263	BRCA	ICGC	PPDY	ITCH	94:97	Mutation rewiring degron network	0.1944
p.G106S	DO233882	GACA	ICGC	PPDY	ITCH	94:97	Mutation rewiring degron network	0.0833
p.P84T	DO228971	LICA	ICGC	PPDY	ITCH	94:97	Mutation rewiring degron network	0.0556
p.Q100K	DO229022	LICA	ICGC	PPDY	ITCH	94:97	Mutation rewiring degron network	0.25
p.Y97H	ACH-000024	Myeloma	CCLE	PPDY	ITCH	94:97	Mutation altering degron motif	0.7229
p.S88G	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	94:97	Mutation blocking phosphorylation signal	0.6111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons