DegronMD - Q6ZN18(AEBP2)

AEBP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D153Y	DO222404	BTCA	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.S142F	DO49974	CESC	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.2778
p.E141K	DO8842	COAD	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation blocking phosphorylation signal	0.6944
p.A138S	DO229027	LICA	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1667
p.M148I	DO229041	LICA	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation altering degron motif	0.7618
p.P143H	DO26423	LUSC	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.3056
p.R138L	DO229257	THCA	ICGC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1667
p.K155E	H9	haematopoietic and lymphoid tissue	COSMIC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation substituting flanking lysine	0.25
p.P134H	MOLT-13	haematopoietic and lymphoid tissue	COSMIC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.0556
p.R152S	NCI-H2110	lung	COSMIC	AASSS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc