PEAK3
UniProt ID: Q6ZS72
Entrez ID: 374872
Protein name: Protein PEAK3
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Probable catalytically inactive kinase (Probable). Interacts with CRK-II and antagonizes CRK-II-signaling. Prevents the formation of CRK-II-dependent membrane ruffling and lamellipodia-like extensions (PubMed:31311869). {ECO:0000269|PubMed:31311869, ECO:0000305|PubMed:31311869}....
FUNCTION: Probable catalytically inactive kinase (Probable). Interacts with CRK-II and antagonizes CRK-II-signaling. Prevents the formation of CRK-II-dependent membrane ruffling and lamellipodia-like extensions (PubMed:31311869). {ECO:0000269|PubMed:31311869, ECO:0000305|PubMed:31311869}.
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GO - Biological processes (BP):
protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]...
protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]
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GO - Molecular function (MF):
protein kinase activity [GO:0004672]; protein self-association [GO:0043621]...
protein kinase activity [GO:0004672]; protein self-association [GO:0043621]
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GO - Cellular component (CC):
actin cytoskeleton [GO:0015629]; focal adhesion [GO:0005925]...
actin cytoskeleton [GO:0015629]; focal adhesion [GO:0005925]
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PEAK3
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*NOTE: the Kaplan plots were collected from OncoLnc