DegronMD - Q6ZTI6(RFLNA)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A45V	SIDM00672	Hepatocellular Carcinoma	GDSC	PPFY	ITCH	38:41	Mutation rewiring degron network	0.2222
p.A45V	SIDM00656	Burkitt's Lymphoma	GDSC	PPFY	ITCH	38:41	Mutation rewiring degron network	0.2222
p.A45V	SIDM00641	Burkitt's Lymphoma	GDSC	PPFY	ITCH	38:41	Mutation rewiring degron network	0.2222

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons