DegronMD - Q86U70(LDB1)

LDB1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G56W	TCGA-D3-A2JK	SKCM	TCGA	PPTY	ITCH	49:52	Mutation rewiring degron network	0.2222
p.P49Q	TCGA-D3-A3CE	SKCM	TCGA	PPTY	ITCH	49:52	Mutation altering degron motif	0.7035
p.T61S	TCGA-DD-AAC8	LIHC	TCGA	PPTY	ITCH	49:52	Mutation blocking phosphorylation signal	0.5278
p.L53P	TCGA-HE-A5NH	KIRP	TCGA	PPTY	ITCH	49:52	Mutation rewiring degron network	0.3056
p.P49S	TCGA-W3-AA1R	SKCM	TCGA	PPTY	ITCH	49:52	Mutation altering degron motif	0.6752
p.F61L	DO8264	COAD	ICGC	PPTY	ITCH	49:52	Mutation blocking phosphorylation signal	0.5278
p.F61L	DO43907	UCEC	ICGC	PPTY	ITCH	49:52	Mutation blocking phosphorylation signal	0.5278
p.T58M	DO233772	GACA	ICGC	PPTY	ITCH	49:52	Mutation rewiring degron network	0.1667
p.T58K	DO229009	LICA	ICGC	PPTY	ITCH	49:52	Mutation rewiring degron network	0.1667
p.D50G	DO22914	LIHC	ICGC	PPTY	ITCH	49:52	Mutation altering degron motif	0.7198
p.R41W	DO52238	LIHC	ICGC	PPTY	ITCH	49:52	Mutation rewiring degron network	0.1111
p.R41L	DO25797	LUAD	ICGC	PPTY	ITCH	49:52	Mutation rewiring degron network	0.1111
p.R41Q	DO220909	MELA	ICGC	PPTY	ITCH	49:52	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc