FUNCTION: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in abso...
FUNCTION: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (PubMed:28420705). {ECO:0000269|PubMed:12618427, ECO:0000269|PubMed:27184406, ECO:0000269|PubMed:28420705}.
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GO - Biological processes (BP):
glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432]...
glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432]
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GO - Molecular function (MF):
2-acylglycerol O-acyltransferase activity [GO:0003846]; diacylglycerol O-acyltransferase activity [GO:0004144]...
2-acylglycerol O-acyltransferase activity [GO:0003846]; diacylglycerol O-acyltransferase activity [GO:0004144]
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GO - Cellular component (CC):
endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; perinuclear endoplasmic reticulum membrane [GO:1990578]...
endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; perinuclear endoplasmic reticulum membrane [GO:1990578]
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