DegronMD - Q8IV13(CCNJL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P320L	TCGA-CW-6087	KIRC	TCGA	PPAY	ITCH	330:333	Mutation rewiring degron network	0.0556
p.P320L	DO20082	KIRC	ICGC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.0556
p.P323L	TCGA-IH-A3EA	SKCM	TCGA	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1389
p.P323L	DO37667	SKCM	ICGC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1389
p.P323H	DO230309	COCA	ICGC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1389
p.P339S	DO233257	GACA	ICGC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1667
p.T342S	DO228470	LICA	ICGC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.0833
p.Q338K	SIDM01958	Esophageal Carcinoma	GDSC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1944
p.T341I	SIDM00429	B-Lymphoblastic Leukemia	GDSC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1111
p.T341I	NALM-6	haematopoietic and lymphoid tissue	COSMIC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1111
p.V331M	HT-115	large intestine	COSMIC	PPAY	ITCH	330:333	Mutation altering degron motif	0.7208
p.T322I	NALM-6	haematopoietic and lymphoid tissue	COSMIC	PPAY	ITCH	330:333	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons