DegronMD - Q8IWK6(ADGRA3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K1263E	SIDM00282	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1256:1260	Mutation substituting flanking lysine	0.3611
p.K1263E	CW-2	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	1256:1260	Mutation substituting flanking lysine	0.3611
p.P1256Q	SIDM01102	Non-Cancerous	GDSC	PVSTT	DEG_SPOP_SBC_1	1256:1260	Mutation altering degron motif	0.7035
p.P1256Q	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	1256:1260	Mutation altering degron motif	0.7035

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons