DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
UniProt ID:
Q8IYB0
Entrez ID:
Protein name:
Putative uncharacterized protein MGC39545
External links:
UniprotKB
HGNC
RefSeq
COSMIC
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Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
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GO - Biological processes (BP):
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GO - Molecular function (MF):
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GO - Cellular component (CC):
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Choose a PDB ID:
Open in full screen with detailed sequence annotations
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Residue number
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Number of mutated samples
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0.5
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1.5
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Phosphorylation sites
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Search:
Degron hit
Class
E3 ligase
Source protein
Location
Detail
PRSLLPPVC
DEG_APCC_DBOX_1
APC,CDC20,FZR1
Putative uncharacterized protein MGC39545
49:57
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Mutation
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Degron hit
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Mutation
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Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc