DegronMD - Q8N1N2(DYNAP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T207A	TCGA-86-A4JF	LUAD	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0833
p.A184S	TCGA-AA-3672	COAD	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0556
p.A184S	TCGA-BR-8370	STAD	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0556
p.T203P	TCGA-AP-A1E0	UCEC	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.1944
p.S198F	TCGA-DA-A1HV	SKCM	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation altering degron motif	0.7982
p.S198F	TCGA-EB-A4IS	SKCM	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation altering degron motif	0.7982
p.D208N	TCGA-EO-A3AY	UCEC	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0556
p.A184T	TCGA-GF-A6C9	SKCM	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0556
p.T196S	TCGA-KU-A66S	HNSC	TCGA	AATTS	DEG_SPOP_SBC_1	194:198	Mutation altering degron motif	0.6005
p.A184V	SIDM02039	Colorectal Carcinoma	GDSC	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.0556
p.A205E	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.1389
p.A205E	EBC-1	lung	COSMIC	AATTS	DEG_SPOP_SBC_1	194:198	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons