DegronMD - Q8N5S9(CAMKK1)

CAMKK1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G56V	TCGA-EO-A3KX	UCEC	TCGA	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation altering degron motif	0.6421
p.G56V	DO219774	UCEC	ICGC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation altering degron motif	0.6421
p.P55S	TCGA-W3-AA1R	SKCM	TCGA	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation altering degron motif	0.6752
p.P55S	DO51275	SKCM	ICGC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation altering degron motif	0.6752
p.A49T	SIDM00035	Thyroid Gland Carcinoma	GDSC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1667
p.A49T	S-117	soft tissue	COSMIC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1667
p.A48P	SIDM00497	Colorectal Carcinoma	GDSC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1389
p.A48S	ACH-000204	Myeloma	CCLE	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1389
p.A48S	LP-1	haematopoietic and lymphoid tissue	COSMIC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1389
p.R47W	ACH-000969	Colon/Colorectal Cancer	CCLE	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1111
p.R47W	KM12	large intestine	COSMIC	PGSTS	DEG_SPOP_SBC_1	55:59	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc