DegronMD - Q8N699(MYCT1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G216S	TCGA-A5-A0G2	UCEC	TCGA	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1667
p.G216S	DO41235	UCEC	ICGC	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1667
p.A231V	TCGA-A5-A0VQ	UCEC	TCGA	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1667
p.A231V	DO42113	UCEC	ICGC	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1667
p.E226K	TCGA-BH-A5J0	BRCA	TCGA	PPAY	ITCH	222:225	Mutation rewiring degron network	0.3056
p.E226K	DO219608	BRCA	ICGC	PPAY	ITCH	222:225	Mutation rewiring degron network	0.3056
p.R214Q	SIDM00007	Other Solid Cancers	GDSC	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1111
p.R214Q	ACH-001550	Skin Cancer	CCLE	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1111
p.R214Q	MCC13	skin	COSMIC	PPAY	ITCH	222:225	Mutation rewiring degron network	0.1111
p.Y225F	SIDM01129	Small Cell Lung Carcinoma	GDSC	PPAY	ITCH	222:225	Mutation altering degron motif	0.8639
p.Y225F	ACH-000816	Lung Cancer	CCLE	PPAY	ITCH	222:225	Mutation altering degron motif	0.8639
p.Y225F	NCI-H524	lung	COSMIC	PPAY	ITCH	222:225	Mutation altering degron motif	0.8639

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons