DegronMD - Q8N6K0(TEX29)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P121H	TCGA-AJ-A3EK	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.0833
p.P121H	DO41584	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.0833
p.S102R	TCGA-B5-A1MV	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.S102R	DO43354	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.S102T	TCGA-B5-A1MV	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.S102T	DO43354	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.S112N	TCGA-QC-A7B5	SARC	TCGA	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7069
p.S112N	DO220239	SARC	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7069
p.K117T	TCGA-VQ-A91S	STAD	TCGA	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation substituting flanking lysine	0.3056
p.K117T	DO222352	STAD	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation substituting flanking lysine	0.3056
p.A105V	DO222813	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.25
p.A108S	DO229041	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7588
p.G122E	DO220851	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.0556
p.A119V	SIDM01649	Non-Cancerous	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A119V	SIDM00297	Non-Small Cell Lung Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A119V	SIDM01172	Acute Myeloid Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A119V	SIDM00184	Melanoma	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A119V	SIDM01728	Endometrial Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A119V	SIDM01685	B-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.G115R	ACH-001569	Skin Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.25
p.L116M	ACH-001853	Bile Duct Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TEX29

UniProt ID: Q8N6K0

Entrez ID: 121793

Protein name: Testis-expressed protein 29

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TEX29 in