STPG4
UniProt ID: Q8N801
Entrez ID: 285051
Protein name: Protein STPG4 (Gonad-specific expression gene protein) (GSE) (Sperm-tail PG-rich repeat-containing protein 4)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). {ECO:0...
FUNCTION: Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). {ECO:0000250|UniProtKB:Q9DAG5}.
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GO - Biological processes (BP):
C-5 methylation of cytosine [GO:0090116]; chromatin organization [GO:0006325]; DNA demethylation of male pronucleus [GO:0044727]; positive regulation of DNA demethylation [GO:1901537]...
C-5 methylation of cytosine [GO:0090116]; chromatin organization [GO:0006325]; DNA demethylation of male pronucleus [GO:0044727]; positive regulation of DNA demethylation [GO:1901537]
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GO - Molecular function (MF):
chromatin binding [GO:0003682]; histone binding [GO:0042393]...
chromatin binding [GO:0003682]; histone binding [GO:0042393]
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GO - Cellular component (CC):
cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; germinal vesicle [GO:0042585]; male pronucleus [GO:0001940]; nucleus [GO:0005634]...
cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; germinal vesicle [GO:0042585]; male pronucleus [GO:0001940]; nucleus [GO:0005634]
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STPG4
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Kaplan plot for STPG4 in
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*NOTE: the Kaplan plots were collected from OncoLnc