DegronMD - Q8N8K9(KIAA1958)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M308T	TCGA-G3-A25U	LIHC	TCGA	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.25
p.M308T	DO22863	LIHC	ICGC	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.25
p.S322N	SIDM00933	Breast Carcinoma	GDSC	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.1389
p.S322N	ACH-000856	Breast Cancer	CCLE	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.1389
p.S322N	CAL-51	breast	COSMIC	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.1389
p.S322T	SIDM01617	Endometrial Carcinoma	GDSC	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.1389
p.S322T	ACH-000994	Endometrial/Uterine Cancer	CCLE	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.1389
p.P324S	SIDM01368	Gastric Carcinoma	GDSC	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.0833
p.P324S	ACH-000255	Gastric Cancer	CCLE	PVSTS	DEG_SPOP_SBC_1	311:315	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons