DegronMD - Q8N9C0(IGSF22)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N780D	TCGA-E6-A2P9	UCEC	TCGA	VPSSS	DEG_SPOP_SBC_1	788:792	Mutation substituting flanking lysine	0.2222
p.N780D	DO43714	UCEC	ICGC	VPSSS	DEG_SPOP_SBC_1	788:792	Mutation substituting flanking lysine	0.2222
p.E782D	DO23282	LINC	ICGC	VPSSS	DEG_SPOP_SBC_1	788:792	Mutation rewiring degron network	0.1667
p.G783D	ACH-000810	Skin Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	788:792	Mutation rewiring degron network	0.1944
p.N780S	ACH-001618	Leukemia	CCLE	VPSSS	DEG_SPOP_SBC_1	788:792	Mutation substituting flanking lysine	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons