DegronMD - Q8NCG7(DAGLB)

DAGLB

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D578N	TCGA-32-2616	GBM	TCGA	PPLY	ITCH	588:591	Mutation rewiring degron network	0.0556
p.P580T	TCGA-AD-6899	COAD	TCGA	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1111
p.A583V	DO225224	BRCA	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1944
p.A583V	DO52562	BRCA	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1944
p.E582K	DO8119	COAD	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1667
p.E582K	DO38723	STAD	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1667
p.E582K	DO43755	UCEC	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1667
p.L589F	DO233641	GACA	ICGC	PPLY	ITCH	588:591	Mutation altering degron motif	0.6981
p.L589F	DO13827	GBM	ICGC	PPLY	ITCH	588:591	Mutation altering degron motif	0.6981
p.L589I	DO229022	LICA	ICGC	PPLY	ITCH	588:591	Mutation altering degron motif	0.7174
p.G591S	DO228869	MALY	ICGC	PPLY	ITCH	588:591	Mutation altering degron motif	0.6993
p.D597H	DO30120	OV	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1667
p.L595I	DO232761	PBCA	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.2222
p.A583T	DO42977	UCEC	ICGC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.1944
p.P592S	SIDM01649	Non-Cancerous	GDSC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.3056
p.P592L	SN12C	kidney	COSMIC	PPLY	ITCH	588:591	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc