DegronMD - Q8NCT3(KIAA0895)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V158L	TCGA-44-2656	LUAD	TCGA	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation altering degron motif	0.5654
p.W164C	TCGA-B0-5092	KIRC	TCGA	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.25
p.H159N	DO233869	GACA	ICGC	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation altering degron motif	0.7423
p.P168S	DO41331	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.1389
p.R150H	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.1389
p.R150H	ACH-002256	Leukemia	CCLE	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.1389
p.R150H	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.1389
p.N171D	RKO	large intestine	COSMIC	PVTSS	DEG_SPOP_SBC_1	157:161	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons