DegronMD - Q8NFV4(ABHD11)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V34L	SIDM00961	Ewing's Sarcoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM00352	Ovarian Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM00267	Biliary Tract Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM00590	Oral Cavity Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM00596	Endometrial Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM01526	Mesothelioma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	SIDM01690	Plasma Cell Myeloma	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000086	Lung Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000210	Bone Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000453	Myeloma	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000472	Head and Neck Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000561	Esophageal Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000719	Ovarian Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000941	Endometrial/Uterine Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-000954	Endometrial/Uterine Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-001517	Endometrial/Uterine Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-001532	Rhabdoid	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.V34L	ACH-002312	Gallbladder Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.25
p.G28C	SIDM01016	T-Lymphoblastic Leukemia	GDSC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28C	ACH-000995	Leukemia	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G28C	Jurkat	haematopoietic and lymphoid tissue	COSMIC	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.0833
p.G46V	ACH-000466	Gastric Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	37:41	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ABHD11

UniProt ID: Q8NFV4

Entrez ID: 83451

Protein name: Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ABHD11 in