DegronMD - Q8TC29(ENKUR)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I14M	TCGA-AJ-A3EK	UCEC	TCGA	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0556
p.I14M	TCGA-B5-A3FA	UCEC	TCGA	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0556
p.I14M	DO52402	UCEC	ICGC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0556
p.I14M	DO41584	UCEC	ICGC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0556
p.P15H	TCGA-D3-A2JP	SKCM	TCGA	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0833
p.P15H	DO47407	SKCM	ICGC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0833
p.P22S	TCGA-YT-A95F	THYM	TCGA	PPRY	ITCH	24:27	Mutation rewiring degron network	0.2778
p.P15T	DO229022	LICA	ICGC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0833
p.K32R	DO220891	MELA	ICGC	PPRY	ITCH	24:27	Mutation substituting flanking lysine	0.3056
p.I14T	DO224633	PACA	ICGC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.0556
p.I30M	SIDM00193	Colorectal Carcinoma	GDSC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.25
p.I30M	ACH-000991	Colon/Colorectal Cancer	CCLE	PPRY	ITCH	24:27	Mutation rewiring degron network	0.25
p.I30M	SNU-81	large intestine	COSMIC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.25
p.E20A	SIDM00225	Melanoma	GDSC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.2222
p.E20A	ACH-002143	Skin Cancer	CCLE	PPRY	ITCH	24:27	Mutation rewiring degron network	0.2222
p.E20A	IST-MEL1	skin	COSMIC	PPRY	ITCH	24:27	Mutation rewiring degron network	0.2222
p.P27S	VMRC-LCD	lung	COSMIC	PPRY	ITCH	24:27	Mutation altering degron motif	0.6752
p.V26G	SC-1	haematopoietic and lymphoid tissue	COSMIC	PPRY	ITCH	24:27	Mutation altering degron motif	0.7532
p.A25V	HCC2998	large intestine	COSMIC	PPRY	ITCH	24:27	Mutation altering degron motif	0.6936

Kaplan plot for ENKUR in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ENKUR

UniProt ID: Q8TC29

Entrez ID: 219670

Protein name: Enkurin

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ENKUR in