DegronMD - Q8TCN5(ZNF507)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q869K	TCGA-EE-A2GE	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.1944
p.Q869K	DO38016	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.1944
p.E858K	TCGA-R3-A69X	BLCA	TCGA	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.2778
p.E858K	DO51902	BLCA	ICGC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.2778
p.S872R	DO1156	BRCA	ICGC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.1111
p.M867I	DO229037	LICA	ICGC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.25
p.E865K	DO233296	NACA	ICGC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.3056
p.V853I	SIDM00319	Melanoma	GDSC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.1389
p.V853I	SIDM00539	Esophageal Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	860:864	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons