DegronMD - Q8WVZ9(KBTBD7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L311V	TCGA-33-4532	LUSC	TCGA	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.2222
p.L311V	DO26626	LUSC	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.2222
p.S326Y	TCGA-AX-A0J0	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.S326Y	DO41133	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.L327I	TCGA-AX-A2HC	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.L327I	DO41572	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.V328L	TCGA-BM-6198	READ	TCGA	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.0833
p.V328L	DO36978	READ	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.0833
p.P313S	TCGA-VQ-A8PP	STAD	TCGA	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.2778
p.P313S	DO51774	STAD	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.2778
p.S317N	DO233885	GACA	ICGC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7069
p.S317N	SIDM00081	Melanoma	GDSC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7069
p.S317N	ACH-000615	Skin Cancer	CCLE	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7069
p.L327F	SIDM01040	Ovarian Carcinoma	GDSC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.L327F	ACH-000574	Ovarian Cancer	CCLE	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.L327F	FU-OV-1	ovary	COSMIC	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.S322T	ACH-000165	Non-Cancerous	CCLE	PNSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.25

Kaplan plot for KBTBD7 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KBTBD7

UniProt ID: Q8WVZ9

Entrez ID: 84078

Protein name: Kelch repeat and BTB domain-containing protein 7

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KBTBD7 in