DegronMD - Q8WZ74(CTTNBP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L401I	TCGA-17-Z026	LUAD	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.25
p.P399H	TCGA-17-Z042	LUAD	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.3056
p.P392A	TCGA-33-4583	LUSC	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2778
p.P392A	DO27112	LUSC	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2778
p.G385V	TCGA-49-4487	LUAD	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.0833
p.G385V	DO24780	LUAD	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.0833
p.G385A	TCGA-55-6969	LUAD	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.0833
p.G385A	DO24586	LUAD	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.0833
p.P402R	TCGA-AJ-A3IA	UCEC	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2222
p.P402R	DO43082	UCEC	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2222
p.P399L	TCGA-EJ-5495	PRAD	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.3056
p.P399L	DO36258	PRAD	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.3056
p.P402S	TCGA-IR-A3LH	CESC	TCGA	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2222
p.P402S	DO44381	CESC	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.2222
p.P408S	DO48216	ESCA	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.0556
p.T388A	DO223089	ESCA	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.1667
p.T391K	DO229037	LICA	ICGC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.25
p.N404S	SIDM00537	Colorectal Carcinoma	GDSC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.1667
p.N404S	GP5d	large intestine	COSMIC	PTSST	DEG_SPOP_SBC_1	394:398	Mutation rewiring degron network	0.1667

Kaplan plot for CTTNBP2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CTTNBP2

UniProt ID: Q8WZ74

Entrez ID: 83992

Protein name: Cortactin-binding protein 2 (CortBP2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CTTNBP2 in