DegronMD - Q92562(FIG4)

FIG4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A743V	TCGA-86-6851	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.0556
p.A743V	DO23798	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.0556
p.D765H	TCGA-CV-A6JM	HNSC	TCGA	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.1111
p.G763W	TCGA-EE-A3AC	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.1667
p.G763W	DO230968	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.1667
p.G763W	DO224621	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.1667
p.G763W	DO37631	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.1667
p.S756N	TCGA-GF-A6C9	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation altering degron motif	0.7069
p.S756N	DO51254	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation altering degron motif	0.7069
p.D761Y	DO229029	LICA	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.2222
p.E759K	DO232858	NACA	ICGC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.2778
p.R766W	SIDM00429	B-Lymphoblastic Leukemia	GDSC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.0833
p.R766W	ACH-000938	Leukemia	CCLE	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.0833
p.R766W	NALM-6	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	753:757	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc