DegronMD - Q92783(STAM)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G212V	TCGA-63-5128	LUSC	TCGA	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.0833
p.R213Q	TCGA-DA-A1IA	SKCM	TCGA	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.0556
p.S209I	DO228971	LICA	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.1667
p.D192Y	DO229029	LICA	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.1389
p.L199F	DO229027	LICA	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation altering degron motif	0.6981
p.D197Y	DO229038	LICA	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.2778
p.Q201L	DO45346	LUAD	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation altering degron motif	0.7765
p.L200I	DO48547	STAD	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation altering degron motif	0.7174
p.A189V	DO47869	STAD	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.0556
p.Q201H	DO41572	UCEC	ICGC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation altering degron motif	0.7582
p.T193A	SIDM00265	Ewing's Sarcoma	GDSC	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.1667
p.T193A	ACH-002104	Bone Cancer	CCLE	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation rewiring degron network	0.1667
p.P199S	ACH-001610	Brain Cancer	CCLE	PSTSS	DEG_SPOP_SBC_1	199:203	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons