DegronMD - Q92918(MAP4K1)

MAP4K1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R438H	TCGA-33-4583	LUSC	TCGA	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.R438H	DO27112	LUSC	ICGC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.S447R	DO229029	LICA	ICGC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation blocking phosphorylation signal	0.75
p.R438C	DO37703	SKCM	ICGC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.R438C	SIDM01175	Other Sarcomas	GDSC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.R438C	ACH-001568	Skin Cancer	CCLE	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.R438C	SW684	soft tissue	COSMIC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.2222
p.R434C	SW684	soft tissue	COSMIC	PPSTS	DEG_SPOP_SBC_1	442:446	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc