DegronMD - Q96EP5(DAZAP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G380V	TCGA-75-6214	LUAD	TCGA	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1389
p.G380V	DO24830	LUAD	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1389
p.S381L	TCGA-CM-6674	COAD	TCGA	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381L	TCGA-E5-A4U1	BLCA	TCGA	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381L	TCGA-EE-A29E	SKCM	TCGA	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381L	DO44061	BLCA	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381L	DO10092	COAD	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381L	DO37831	SKCM	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.P366S	TCGA-EE-A2GN	SKCM	TCGA	PPSY	ITCH	370:373	Mutation rewiring degron network	0.2222
p.P366S	DO37896	SKCM	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.2222
p.G360A	DO217887	BRCA	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.0556
p.V371F	DO228978	LICA	ICGC	PPSY	ITCH	370:373	Mutation altering degron motif	0.7068
p.P363S	DO220902	MELA	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1389
p.G383A	DO35172	PACA	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.0556
p.G383A	DO228012	SKCA	ICGC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.0556
p.G362C	SIDM01004	Chronic Myelogenous Leukemia	GDSC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.G362C	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.G362S	SIDM00789	Colorectal Carcinoma	GDSC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.G362S	HCT-15	large intestine	COSMIC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S368G	SIDM01608	Endometrial Carcinoma	GDSC	PPSY	ITCH	370:373	Mutation rewiring degron network	0.2778
p.D365A	ACH-000059	Leukemia	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1944
p.S381W	ACH-000373	Leukemia	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381W	ACH-001081	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381W	ACH-002186	Pancreatic Cancer	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381W	ACH-002273	Leukemia	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381W	ACH-002310	Liposarcoma	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111
p.S381W	ACH-002371	Non-Cancerous	CCLE	PPSY	ITCH	370:373	Mutation rewiring degron network	0.1111

Kaplan plot for DAZAP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DAZAP1

UniProt ID: Q96EP5

Entrez ID: 26528

Protein name: DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DAZAP1 in