DegronMD - Q96IZ7(RSRC1)

RSRC1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P276L	TCGA-OD-A75X	SKCM	TCGA	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.0833
p.P276L	DO48601	SKCM	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.0833
p.R269T	DO50437	ESAD	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.2778
p.V275L	DO228948	LICA	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.1111
p.R273L	DO23174	LINC	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.1667
p.K267M	DO26250	LUAD	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation altering degron motif	0.8062
p.K253R	DO228253	MALY	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation substituting flanking lysine	0.1667
p.K253R	SIDM01218	Other Solid Cancers	GDSC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation substituting flanking lysine	0.1667
p.K253R	JEG-3	placenta	COSMIC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation substituting flanking lysine	0.1667
p.A261V	DO219480	SKCM	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.2778
p.A261V	DO41746	UCEC	ICGC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.2778
p.G268E	SIDM00516	Melanoma	GDSC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.3056
p.G268E	ACH-002166	Skin Cancer	CCLE	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.3056
p.G268E	MZ7-mel	skin	COSMIC	ATSTS	DEG_SPOP_SBC_1	263:267	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc