DegronMD - Q96JG8(MAGED4; MAGED4B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A730V	TCGA-AP-A1DV	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	716:720	Mutation rewiring degron network	0.0556
p.S717R	TCGA-B5-A3FC	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	716:720	Mutation altering degron motif	0.6316

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons